Health△ Caution

Experimental injection makes fat cells self-destruct in early trials

Reported byScienceAlert ↗·Sourced by Goodlede

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What backs it

CBL-514, a new drug administered by injection, killed off fat cells in early clinical trials involving 280 participants. In a subset of 41 participants, the injection reduced visceral fat by an average of 12%, while placebo recipients' visceral fat increased by 5.68%. Animal tests showed rats treated with CBL-514 combined with the GLP-1 drug tirzepatide lost more weight and regained less when treatment stopped.

Worth noting

Results are from conference presentations and company announcements, not yet peer-reviewed. Testing has been in phase 2 clinical trials in humans and animal tests; safety and long-term effectiveness remain to be established.

Notable but earlyEarly△ Caution

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Experimental injection makes fat cells self-destruct in early trials

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