Common glaucoma test can save eyesight before point of no return

An international team at QIMR Berghofer and Flinders University has improved a polygenic risk score test for open-angle glaucoma using data from 6 million people (up from 8,000 in the 2020 version), identifying those in the highest 10% of genetic risk as 10 times more likely to develop the disease, enabling early intervention before sight loss occurs.

The test has been developed and validated on data; clinical adoption and outcomes in routine practice remain to be demonstrated.