Sugar-Coated Nanoparticles Shrink Deadly Brain Tumors in Mice
Reported byScienceAlert ↗·Sourced by Goodlede
Oregon State University researchers published a mouse-model study in the Journal of Controlled Release showing that mannose-coated nanoparticles delivering PTEN-encoding mRNA reduced glioblastoma tumor burden from an average 52% to 2.3% of brain volume and extended median survival from 33 to 49 days without measurable organ toxicity.
This is a mouse study; effectiveness in human glioblastoma patients remains to be tested.
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