Health✓ Verified

Drug Stops 90% of Pancreatic Cancer Migration in Lab Tests

Reported byScienceAlert ↗·Sourced by Goodlede

What backs it

A team from Florida A&M University College of Pharmacy and Pharmaceutical Sciences tested polyisoprenylated cysteinyl amide inhibitors (PCAIs) on pancreatic cancer cells with KRAS mutations. The compound NSL-YHJ-2-27 blocked more than 90 percent of cancer cell migration at low concentrations and triggered programmed cell death in 3D tumor models, offering a potential targeted therapy for KRAS-driven pancreatic cancers previously considered 'undruggable.'

Worth noting

Results are from lab-grown cell models and miniature 3D tumors; human clinical trials would be required to determine safety and efficacy in patients.

Notable but earlyModerate✓ Verified

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