Chronic pain eased by a common sleep supplement

University of Sydney meta-analysis of 23 randomized controlled trials involving 2,028 adults found melatonin reduced chronic pain by ~9–10 points on a 0–100 scale across low back pain, osteoarthritis, fibromyalgia, and postoperative conditions—equivalent to standard pain medications but safer.

Melatonin is not a replacement for all pain medications; dosing varies by condition and requires medical consultation.