A hidden immune backup system could supercharge mRNA cancer vaccines
Reported byScienceDaily ↗·Sourced by Goodlede
Researchers at Washington University School of Medicine discovered that mRNA cancer vaccines remain highly effective even when a long-assumed essential immune cell (cDC1) is missing, because a related immune cell (cDC2) steps in to trigger tumor-fighting responses, offering new mechanistic insights for vaccine optimization.
Research is in mouse models; human trials remain in early phases.
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